Artemisinin, a sesquiterpene lactone endoperoxide compound derived from Artemisia annua L., is highly effective against multi-drug resistant Plasmodium spp. In addition to its antimalaria activity, artemisinin now has been known for its various medicinal properties such as antiviral and anti-cancer activities. Nevertheless, one of the major challenges facing artemisinin production nowadays is its low yield per dry weight. Thus, in this study, enhancement of artemisinin content in plant parts produced from different culturing systems was investigated by using plant bioregulator in order to provide other alternative sources of artemisinin production besides the field grown plants. Our result showed the potential use of CPPU in promoting artemisinin accumulation in both the hairy root system and transplanted pots of A. annua. It was also suggested that using effective stimulators with appropriate culturing system could enhance not only production of the target compound but also other useful compounds.
